In sequencing by hybridization (SBH),
one has to reconstruct a sequence
from its $l$-long substrings.
SBH was proposed as
an alternative to
gel-based
DNA sequencing approaches, but in its original form the method
is
not competitive.
Positional SBH (PSBH) is a recently proposed
enhancement ... more >>>

The breakpoint distance between two $n$-permutations is the number
of pairs that appear consecutively in one but not in the other. In
the median problem for breakpoints one is given a set of
permutations and has to construct a permutation that minimizes the
sum of breakpoint ... more >>>