We prove that $\mathrm{deg}(f) \leq 2 \, \mathrm{rdeg}(f)^4$ for every Boolean function $f$, where $\mathrm{deg}(f)$ is the degree of $f$ and $\mathrm{rdeg}(f)$ is the rational degree of $f$. This resolves the second of the three open problems stated by Nisan and Szegedy, and attributed to Fortnow, in 1994.